49ers vs Seahawks tipped off the 2025 NFL season in a dramatic Week 1 clash, with the San Francisco 49ers eking out a 17‑13 win over the Seattle Seahawks at Lumen Field.
Opening Drive Sets Tone
The focus instantly shifted to 49ers vs Seahawks as Brock Purdy led a commanding 14‑play, 95‑yard drive on the game’s first possession, culminating in a 5‑yard touchdown to George Kittle. WR Ricky Pearsall delivered impact early with back-to-back catches gaining 26 and 13 yards—though Kittle would later leave due to injury.49ers.comSan Francisco Chronicle1
Knockouts and Comebacks
The drama of 49ers vs Seahawks intensified as multiple key players exited early. Star tight end George Kittle left the game with a hamstring injury after his touchdown reception. Jauan Jennings also suffered a shoulder injury, though Trent Williams did return.San Francisco ChronicleThe Sun
Despite early setbacks, the 49ers leaned heavily on Christian McCaffrey, who responded with 142 total yards (69 rushing, 73 receiving), proving vital to the offense’s rhythm.Niners Nation1New York Post
Purdy & Pearsall: A Connection Worth Noting
The 49ers vs Seahawks narrative spotlighted an emergent chemistry between Purdy and Pearsall. Pearsall caught four balls for 108 yards—including two key double-moves of 26 and 45 yards—setting up both touchdowns.San Francisco Chronicle
Defense Holds Firm, But Special Teams Falter
Seattle’s defense delivered under pressure, with standout plays including a blocked field goal by Julian Love, two interceptions, and relentless short-yardage stops.seahawks.comNiners Nation
On the other hand, special teams emerged as the 49ers’ Achilles heel. Kicker Jake Moody missed two field goals, drawing an F grade for the unit, despite overall offense and defense earning commendable marks.San Francisco Chronicle
Game-Winning Drive Seals It
With time running out, Purdy orchestrated a crucial drive featuring a long strike to Pearsall and a clutch touchdown pass to Jake Tonges—his third-ever NFL catch—which ultimately provided the decisive margin.49ers.com1Niners Nation
The showdown concluded when Nick Bosa executed a strip-sack on Sam Darnold, recovering the live ball and sealing the 17‑13 win.49ers.com1Niners Nation
Seahawks’ Perspective
In 49ers vs Seahawks, the Seahawks rallied late behind QB Sam Darnold (16/23, 150 yards) but were undone on the final possession by Bosa’s defensive play.seahawks.comNBC SportsYahoo Sports
Rivalry Lives On
This season opener bespoke the enduring intensity of the 49ers vs Seahawks rivalry. The Seahawks had led the all-time series 31–24, and this win starts a new streak for San Francisco.Wikipedia
Key Takeaways from 49ers vs Seahawks
| Highlight | Detail |
|---|---|
| Quarterback play | Purdy: 26/35, 277 yards, 2 TDs, 2 INTs; late-game resilience |
| Injuries | Kittle (hamstring), Jennings (shoulder) exit early |
| McCaffrey’s impact | 142 total yards, dual-threat effectiveness |
| Special Teams | 2 missed FGs by Moody; weakest performer |
| Defensive execution | Bosa fumble, Seattle stops, but unable to counter decisive strike |
Final Thoughts: 49ers vs Seahawks
The 49ers vs Seahawks season opener delivered classic NFL drama. Despite injury setbacks and shaky kicking, San Francisco’s offense—anchored by Purdy, Pearsall, and McCaffrey—combined with signature defensive pressure to come away with a gritty win. For Seattle, a valiant defensive stand and a few near-misses defined a game they nearly stole.
Looking ahead, the 49ers must monitor injury recoveries, while the Seahawks will search for offensive cohesion in Darnold’s first start. Rivalry renewed, storylines deepened—49ers vs Seahawks sets the bar high for Week 2.
